Berberine 500 delivers 500 mg of berberine HCl (97%) per capsule, derived from non-GMO botanical sources. Berberine supports healthy blood glucose and lipid metabolism within normal limits by activating AMPK, a key enzyme for energy and fat regulation.* Clinical studies have evaluated berberine's effect on healthy glucose balance, triglycerides, cholesterol, and body composition.* Berberine also promotes a balanced gut microbiome, which contributes to gastrointestinal and immune health.* Berberine is well-tolerated and research-supported.*