L-Methylfolate, an important methyl donor, provides a bioactive form of folate that bypasses genetic conversion barriers to support methylation and mood balance.* Unlike folic acid, L-Methylfolate does not require conversion by the MTHFR enzyme, a function that may be impaired by genetic variations present in about half the population.* Our 5 mg potency active L-Methylfolate provides essential support for cardiovascular function.* It is also ideal for those seeking advanced folate support for energy and metabolic health.*