SAMe is a versatile molecule used as a critical methyl donor throughout the body aiding in cellular protection.* SAMe 200 mg supports healthy methylation, mood, and neurotransmitter synthesis.* It also promotes joint comfort and liver function as part of its broad metabolic activity.* This clean, bioactive formula offers comprehensive support for cellular and emotional well-being.* Though versatile and effective, the molecule can be unstable. Our formula combines SAMe with calcium making it less sensitive to humidity and temperature. This means you can get the benefits of SAMe without a coated tablet or hassling with refrigeration. To promote maximum efficacy, we provide our clean version of SAMe in acid resistant capsules for release in the intestine.