Not recommended for those under 18 years of age. If taking antidepressant medication, particularly antidepressants such as MAO inhibitors or selective serotonin reuptake inhibitors (SSRIs), avoid use. If you have a medical condition—including symptomatic gastrointestinal disorders, or are taking medication—including over-the-counter cold medicine and high blood pressure medicines, consult your healthcare practitioner before use. Use with caution when driving or operating machinery, may cause drowsiness. Keep out of the reach of children.