A trio of supplements that help manage stress*Thorne’s Stress Management Bundle contains three nutritional supplements that can help with stress management, as well as providing support for healthy adrenal function — Stress B-Complex, PharmaGABA-250, and Phytisone®.*Too much daily stress will eventually take a toll on our body. The constant low-level stress that most of us encounter daily – combined with environmental pollution and diets high in refined carbohydrates – can overstimulate and overtax the adrenal glands, which in turn can damage the immune, cardiovascular, neurological, and endocrine systems, and eventually, a person’s long-term health. Thorne’s Stress Management Bundle provides comprehensive benefits by optimizing the response of the adrenal glands to stress, by supporting immune function, and by promoting a calm state of mind and restful sleep.*Stress B-Complex contains an optimal balance of essential B vitamins, with extra vitamin B5 to support healthy adrenal and immune function.*PharmaGABA-250 features a natural source of the inhibitory neurotransmitter – GABA. GABA supports restful sleep, acts as a "brake" on stress, and promotes a focused but calm state of mind.* Clinical studies show this natural form of GABA in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of  alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus.* Other studies show reduced pupil diameter and heart rate, and a reduction in the levels of two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of enhanced relaxation.*Phytisone® is a unique, non-glandular formula of botanicals and nutrients that help optimize the adrenal gland's response to stress and also help reduce fatigue.*Thorne's logo, text, trademarks, graphics, videos and photo images are the property of Thorne and are used with permission. Copyright © 2023*FDA Disclaimer: The information about this product and statements made are provided by the manufacturer, except customer reviews which are not evaluated. See www.thorne.com for information about the relationship between this product and any claims made. Results may vary from person to person based on body size and other factors, and the effectiveness is not guaranteed for you. Always seek the advice of your healthcare professional about taking dietary, nutritional, herbal or homeopathic supplements.